Operational Expertise Anchored in Broad Analgesia Experience

Syneos Health has an established reputation for our work in pain management including the design, feasibility, execution, analysis and interpretation of studies in a variety of acute, sub-acute and chronic pain disorders, rare indications, and pediatric pain.


We get you results.


Our 100% therapeutic alignment combined with our Customer Relations Executive (CRE) model means that everyone we dedicate to your study team, from project leads to clinical research associates (CRAs), is steeped in the intricacies of analgesia studies and their successful execution, resulting in optimal project delivery and impact on sites.


  • We have co-designed and conducted multiple Phase 3 acute and chronic pain studies leading to NDAs, including 3 recent agency approvals; completed numerous positive proof-of-concept studies (POCs) leading to pivotal programs in analgesia indications
  • We have global experience in managing studies with controlled substances.
  • Applying robust rater training and eligibility surveillance strategies via our in-house Clinical Surveillance and Training (CST) team help mitigate the placebo effect that affects analgesia studies and ensure quality data
  • Our comprehensive experience with multiple electronic clinical outcome assessment (eCOA) providers and systems expedites instrument selection, validation, and translation, global diary set-up, training and data flow management.
  • Our experience also includes set up and oversight of nerve conduction velocity (NCV) testing and quantitative sensory testing (QST) measures in global studies in multiple indications.


Analgesia Study Experience Summary by Class (Since 2015)
CNS Analgesia Experience Data 2015-2020

Our relationships with analgesia key opinion leaders (KOLs) and clinical research sites are second to none.

Our therapeutic alignment means that we are able to engage with focus and peer-to-peer scientific expertise to develop deep relationships with key opinion leaders, investigators and sites.

Our Catalyst Pain Network provides you more than 20 proven US sites for conduct of different post-surgical pain models, and we have extensive chronic pain site networks within most world geographies for access to chronic pain patient populations.